John Howl,
Professor $150,000 / 2 Years Awarded January 2023 |
John Howl, PhDUniversity of Wolverhampton
Wolverhampton, England About
Dr. John Howl is a Professor at the University of Wolverhampton exploring the design, microwave-enhanced synthesis, and applications of cell-penetrating peptides. Our Grant
Our support for the team facilitates the optimization of STOPSPERM bioportides, which are small peptides that can interrupt protein-protein interactions required for fertility. This global collaboration includes investigators Margarida Fardilha at the University of Aveiro, Portugal, David Craik at the University of Queensland in Australia, and Erick Silva at the, Institute of Biosciences, São Paulo State University (UNESP), Botucatu-SP, Brazil. |
Publications
Howl, J., Silva, J. V., Fardilha, M., & Jones, S. (2022). Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides: The Genesis of STOPSPERM Bioportides. Methods in molecular biology (Clifton, N.J.), 2383, 293–306. https://doi.org/10.1007/978-1-0716-1752-6_20
Silva, J. V., Freitas, M. J., Santiago, J., Jones, S., Guimarães, S., Vijayaraghavan, S., Publicover, S., Colombo, G., Howl, J., & Fardilha, M. (2021). Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility. Fertility and sterility, 115(2), 348–362. https://doi.org/10.1016/j.fertnstert.2020.08.013
Howl, J., Silva, J. V., Fardilha, M., & Jones, S. (2022). Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides: The Genesis of STOPSPERM Bioportides. Methods in molecular biology (Clifton, N.J.), 2383, 293–306. https://doi.org/10.1007/978-1-0716-1752-6_20
Silva, J. V., Freitas, M. J., Santiago, J., Jones, S., Guimarães, S., Vijayaraghavan, S., Publicover, S., Colombo, G., Howl, J., & Fardilha, M. (2021). Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility. Fertility and sterility, 115(2), 348–362. https://doi.org/10.1016/j.fertnstert.2020.08.013
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Meet MCI's Grantees & Fellows!
Our grantees and fellows represent some of the finest minds in the male contraception research community from around the world.
At Male Contraceptive Initiative, we prioritize funding research that aligns with our mission of driving male contraception closer to clinical trials. We strategically allocate our resources to support a diverse range of projects, focusing on non-hormonal and reversible methods that have the potential to meet the needs of a broader population. Our goal is to catalyze progress in this field and bring innovative male birth control options to market.
Discover the innovative research being conducted by our grantees and fellows by clicking on the buttons below:
At Male Contraceptive Initiative, we prioritize funding research that aligns with our mission of driving male contraception closer to clinical trials. We strategically allocate our resources to support a diverse range of projects, focusing on non-hormonal and reversible methods that have the potential to meet the needs of a broader population. Our goal is to catalyze progress in this field and bring innovative male birth control options to market.
Discover the innovative research being conducted by our grantees and fellows by clicking on the buttons below:
