John Howl,
Professor $150,000 / 2 Years Awarded January 2023 |
John Howl, PhDUniversity of Wolverhampton
Wolverhampton, England About
Dr. John Howl is a Professor at the University of Wolverhampton exploring the design, microwave-enhanced synthesis, and applications of cell-penetrating peptides. Our Grant
Our support for the team facilitates the optimization of STOPSPERM bioportides, which are small peptides that can interrupt protein-protein interactions required for fertility. This global collaboration includes investigators Margarida Fardilha at the University of Aveiro, Portugal, David Craik at the University of Queensland in Australia, and Erick Silva at the, Institute of Biosciences, São Paulo State University (UNESP), Botucatu-SP, Brazil. |
Publications
Howl, J., Silva, J. V., Fardilha, M., & Jones, S. (2022). Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides: The Genesis of STOPSPERM Bioportides. Methods in molecular biology (Clifton, N.J.), 2383, 293–306. https://doi.org/10.1007/978-1-0716-1752-6_20
Silva, J. V., Freitas, M. J., Santiago, J., Jones, S., Guimarães, S., Vijayaraghavan, S., Publicover, S., Colombo, G., Howl, J., & Fardilha, M. (2021). Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility. Fertility and sterility, 115(2), 348–362. https://doi.org/10.1016/j.fertnstert.2020.08.013
Howl, J., Silva, J. V., Fardilha, M., & Jones, S. (2022). Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides: The Genesis of STOPSPERM Bioportides. Methods in molecular biology (Clifton, N.J.), 2383, 293–306. https://doi.org/10.1007/978-1-0716-1752-6_20
Silva, J. V., Freitas, M. J., Santiago, J., Jones, S., Guimarães, S., Vijayaraghavan, S., Publicover, S., Colombo, G., Howl, J., & Fardilha, M. (2021). Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility. Fertility and sterility, 115(2), 348–362. https://doi.org/10.1016/j.fertnstert.2020.08.013
